The PSA test can miss prostate cancer. For example, one major study showed that 1 in 7 men with a normal PSA level may have prostate cancer, and 1 in 50 men with a normal PSA level may have a fast-growing cancer. If your PSA level is raised you may need a biopsy. This can cause side effects, such as pain, infection and bleeding.
A continuous rise: PSA levels that continue to rise after two or more tests may mean you have cancer. But the PSA level alone doesnt determine if you have cancer or not. Two men can even have the same PSA levels but different risks of prostate cancer. And a high PSA level may reflect prostate problems that arent cancer.
Last Reviewed: June 10, 2022. For the majority of men, prostate cancer is treatable and curable and does not come back after initial treatment. However, about 25%–33% of men with prostate cancer will experience a recurrence of their cancer after surgery or radiation. Some of these men can still be cured with additional treatment, but some men

A prostate-specific antigen (PSA) test measures the amount of PSA in your body. PSA is a protein that your prostate gland makes. Normal and cancerous prostate tissue make PSA. However, prostate cancer tends to produce it in higher amounts. High PSA levels may indicate prostate cancer.

Men can have prostate cancer even if they have a normal PSA level. But cancer is more likely with an elevated PSA level. When PSA levels are: Below 4: 15% chance of prostate cancer. Between 4 and 10 (the borderline range): 25% chance of prostate cancer. Above 10: More than 50% chance of having prostate cancer.
Researchers found that compared with the people doing their usual lower-intensity exercise, those in the HIIT group had lower prostate-specific antigen (PSA) levels, lower PSA velocities (the rate of change in PSA levels over time), and had slower prostate cancer cell growth. They also had better cardiovascular fitness.
The introduction of prostate-specific antigen (PSA) as a reliabletumor marker for prostate cancer brought significant changes in theend points used for outcome reporting after therapy. With regard to adefinition of failure after radiation, a consensus was reached in 1996that took into account the particular issues of an intact prostate aftertherapy. Over the next several years, the consensus
It’s anxiety provoking to have to wait for one or more repeat blood tests to find out if PSA is coming back down. Thankfully, a presentation by Monaco, et al. [iii] at the 2022 annual meeting of the American Urological Association offers some real clues—not red herrings—to help tell whether a rising PSA is more likely a bounce than
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    • can psa levels go down